Endocannabinoids mediate muscarinic acetylcholine receptor-dependent long-term depression in the adult medial prefrontal cortex

Endocannabinoids mediate muscarinic acetylcholine receptor-dependent long-term depression in the adult medial prefrontal cortex

Cholinergic inputs into the prefrontal cortex (PFC) are associated with attention and cognition; however there is evidence that acetylcholine also has a role in PFC dependent learning and memory. Muscarinic acetylcholine receptors (mAChR) in the PFC can induce synaptic plasticity, but the underlying...

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Bibliographic Details
Main Authors: Henry Giles Stratten Martin, Axel eBernabeu, Olivier eLassalle, Clement eBouille, Corinne eBeurrier, Anne-Laure ePelissier-Alicot, Olivier Jacques José Manzoni
Format: Article
Language:English
Published: Frontiers Media S.A. 2015-12-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Prefrontal Cortex
Long-term depression
CB1 receptor
endocannabinoid system
muscarinic receptors
acetylcholine receptor
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00457/full

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http://journal.frontiersin.org/Journal/10.3389/fncel.2015.00457/full

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