Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders

Pharmacological targeting of bone marrow mesenchymal stromal/stem cells for the treatment of hematological disorders

Abstract The therapeutic effects of mesenchymal stromal/stem cells (MSCs) are mainly based on three characteristics: immunomodulation, tissue regeneration, and hematopoietic support. Cell therapy using culture-expanded MSCs is effective in some intractable bone and hemato-immune disorders; however,...

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Bibliographic Details
Main Authors: Noriko Sugino, Tatsuo Ichinohe, Akifumi Takaori-Kondo, Taira Maekawa, Yasuo Miura
Format: Article
Language:English
Published: BMC 2017-04-01
Series:Inflammation and Regeneration
Subjects:
Mesenchymal stromal/stem cell
Hematopoiesis
Regeneration
Immunomodulation
Pharmacological modification
Cell therapy
Online Access:http://link.springer.com/article/10.1186/s41232-017-0038-5

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http://link.springer.com/article/10.1186/s41232-017-0038-5

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