A Prostate Cancer Risk Element Functions as a Repressive Loop that Regulates HOXA13

Summary: Prostate cancer (PCa) is the leading cancer among men in the United States, with genetic factors contributing to ∼42% of the susceptibility to PCa. We analyzed a PCa risk region located at 7p15.2 to gain insight into the mechanisms by which this noncoding region may affect gene regulation a...

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Bibliographic Details
Main Authors: Zhifei Luo, Suhn Kyong Rhie, Fides D. Lay, Peggy J. Farnham
Format: Article
Language:English
Published: Elsevier 2017-11-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S221112471731495X