3D model of lamprey estrogen receptor with estradiol and 15alpha-hydroxy-estradiol.

BACKGROUND:Lamprey, basal vertebrate, is an important model system for understanding early events in vertebrate evolution. Lamprey contains orthologs of the estrogen receptor [ER], progesterone receptor and corticoid receptor. A perplexing property of lamprey is that 15alpha-hydroxy-steroids are act...

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Bibliographic Details
Main Authors: Michael E Baker, David J Chang, Charlie Chandsawangbhuwana
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-06-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2698217?pdf=render