HDAC9 is an epigenetic repressor of kidney angiotensinogen establishing a sex difference

Abstract Background Sexual difference has been shown in the pathogenesis of chronic kidney disease induced by hypertension. Females are protected from hypertension and related end-organ damage. Augmentation of renal proximal tubular angiotensinogen (AGT) expression can promote intrarenal angiotensin...

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Bibliographic Details
Main Authors: Camille T. Bourgeois, Ryousuke Satou, Minolfa C. Prieto
Format: Article
Language:English
Published: BMC 2017-05-01
Series:Biology of Sex Differences
Subjects:
Online Access:http://link.springer.com/article/10.1186/s13293-017-0140-z