Layer‐by‐layer nanoparticles for novel delivery of cisplatin and PARP inhibitors for platinum‐based drug resistance therapy in ovarian cancer

Layer‐by‐layer nanoparticles for novel delivery of cisplatin and PARP inhibitors for platinum‐based drug resistance therapy in ovarian cancer

Abstract Advanced staged high‐grade serous ovarian cancer (HGSOC) is the leading cause of gynecological cancer death in the developed world, with 5‐year survival rates of only 25–30% due to late‐stage diagnosis and the shortcomings of platinum‐based therapies. A Phase I clinical trial of a combinati...

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Bibliographic Details
Main Authors: Lawrence B. Mensah, Stephen W. Morton, Jiahe Li, Haihua Xiao, Mohiuddin A. Quadir, Kevin M. Elias, Emily Penn, Aysen K. Richson, Paiman Peter Ghoroghchian, Joyce Liu, Paula T. Hammond
Format: Article
Language:English
Published: Wiley 2019-05-01
Series:Bioengineering & Translational Medicine
Subjects:
BMN 673
cisplatin
layer‐by‐layer
nanomedicine
nanoparticles
olaparib
Online Access:https://doi.org/10.1002/btm2.10131

Internet

https://doi.org/10.1002/btm2.10131

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