Neurotoxins and their binding areas on voltage-gated sodium channels

Voltage-gated Sodium Channels (VGSCs) are large transmembrane proteins that conduct sodium ions across the membrane and by doing so they generate signals of communication between many kinds of tissues. They are responsible for the generation and propagation of action potentials in excitable cells,...

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Bibliographic Details
Main Authors: Marijke eStevens, Steve ePeigneur, Jan eTytgat
Format: Article
Language:English
Published: Frontiers Media S.A. 2011-11-01
Series:Frontiers in Pharmacology
Subjects:
Online Access:http://journal.frontiersin.org/Journal/10.3389/fphar.2011.00071/full