Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus.

Gene network analysis of bone marrow mononuclear cells reveals activation of multiple kinase pathways in human systemic lupus erythematosus.

Gene profiling studies provide important information for key molecules relevant to a disease but are less informative of protein-protein interactions, post-translational modifications and regulation by targeted subcellular localization. Integration of genomic data and construction of functional gene...

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Main Authors: Magdalene Nakou, George Bertsias, Ilias Stagakis, Michael Centola, Ioannis Tassiulas, Maria Hatziapostolou, Iraklis Kritikos, George Goulielmos, Dimitrios T Boumpas, Dimitrios Iliopoulos
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2010-10-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2954787?pdf=render

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http://europepmc.org/articles/PMC2954787?pdf=render

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