Regulation of NLRP3 Inflammasome by Phosphorylation

Regulation of NLRP3 Inflammasome by Phosphorylation

The cytosolic pattern recognition receptor (PRR) NOD-like receptor family, pyrin domain containing 3 (NLRP3) senses a wide range of pathogen-associated molecular patterns (PAMPs) and damage-associated molecular patterns (DAMPs). Upon activation, NLRP3 triggers the assembly of inflammasome via the se...

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Bibliographic Details
Main Authors: Nan Song, Tao Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2018-10-01
Series:Frontiers in Immunology
Subjects:
innate immunity
inflammasome
NLRP3
phosphorylation
kinase
phosphatase
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2018.02305/full

Internet

https://www.frontiersin.org/article/10.3389/fimmu.2018.02305/full

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