Promoter activity of Merkel cell Polyomavirus variants in human dermal fibroblasts and a Merkel cell carcinoma cell line

Promoter activity of Merkel cell Polyomavirus variants in human dermal fibroblasts and a Merkel cell carcinoma cell line

Abstract Background Merkel cell polyomavirus (MCPyV) is a human polyomavirus that establishes a life-long harmless infection in most individuals, with dermal fibroblasts believed to be the natural host cell. However, this virus is the major cause of Merkel cell carcinoma (MCC), an aggressive skin ca...

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Bibliographic Details
Main Authors: Ibrahim Abdulsalam, Kashif Rasheed, Baldur Sveinbjørnsson, Bernhard Ehlers, Ugo Moens
Format: Article
Language:English
Published: BMC 2020-04-01
Series:Virology Journal
Subjects:
Non-coding control region
Large T-antigen
Luciferase assay
MCC13 cells
MCPyV
Mutations
Online Access:http://link.springer.com/article/10.1186/s12985-020-01317-x

Internet

http://link.springer.com/article/10.1186/s12985-020-01317-x

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