Insula Volume and Salience Network Are Associated with Memory Decline in Parkinson Disease: Complementary Analyses of Voxel-Based Morphometry versus Volume of Interest

Objective. We investigated structural brain change in subjects with a clinical diagnosis of Parkinson disease with mild cognitive impairment (PD-MCI) and examined its relationship with memory impairment. Methods. Twenty-three PD-MCI patients were enrolled and underwent cognitive evaluation and 3-dim...

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Bibliographic Details
Main Authors: Yan-Ting Lu, Wen-Neng Chang, Chiung-Chih Chang, Cheng-Hsien Lu, Nai-Ching Chen, Chi-Wei Huang, Wei-Che Lin, Ya-Ting Chang
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Parkinson's Disease
Online Access:http://dx.doi.org/10.1155/2016/2939528