Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC

Cytoplasmic TRAIL-R1 is a positive prognostic marker in PDAC

Abstract Background The death receptors TRAIL-R1 and TRAIL-R2 are frequently overexpressed in cancer and there is an emerging evidence for their important role in malignant progression, also in the case of pancreatic ductal adenocarcinoma (PDAC). In their canonical localization at the plasma membran...

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Bibliographic Details
Main Authors: Jan-Paul Gundlach, Charlotte Hauser, Franka Maria Schlegel, Christine Böger, Christian Röder, Christoph Röcken, Thomas Becker, Jan-Hendrik Egberts, Holger Kalthoff, Anna Trauzold
Format: Article
Language:English
Published: BMC 2018-07-01
Series:BMC Cancer
Subjects:
TRAIL-R1
Death receptor
Immunhistology
Pancreatic cancer
Online Access:http://link.springer.com/article/10.1186/s12885-018-4688-8

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http://link.springer.com/article/10.1186/s12885-018-4688-8

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