Deficits in the IgG+ memory B‐cell recovery after anthracycline treatment is confined to the spleen of rhesus macaques

Deficits in the IgG+ memory B‐cell recovery after anthracycline treatment is confined to the spleen of rhesus macaques

Abstract Objectives Loss of vaccine‐induced antibodies (Abs) after chemotherapy against paediatric acute lymphoblastic leukaemia (ALL) is common and often necessitates re‐immunisation after cessation of treatment. Even so, some ALL survivors fail to mount or to maintain protective Abs. Germinal cent...

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Bibliographic Details
Main Authors: Gintare Lasaviciute, Andréas L Bricaud, Fredrika Hellgren, Hanna M Ingelman‐Sundberg, Staffan Eksborg, Margreet Jonker, Krista G Haanstra, Ida Hed Myrberg, Eva Sverremark‐Ekström, Karin Loré, Shanie Saghafian‐Hedengren, Anna Nilsson
Format: Article
Language:English
Published: Wiley 2020-01-01
Series:Clinical & Translational Immunology
Subjects:
anthracycline
de novo and booster vaccine
memory B‐cell response
rhesus macaque
secondary lymphoid organs
Online Access:https://doi.org/10.1002/cti2.1150

Internet

https://doi.org/10.1002/cti2.1150

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