Activation of aryl hydrocarbon receptor (AhR) in mesenchymal stem cells modulates macrophage polarization in asthma

Macrophage polarization has been demonstrated to exert a vital role on asthma pathogenesis. Mesenchymal stem cells (MSC) have the capacity to modulate macrophage differentiation from a pro-inflammatory M1 phenotype toward an anti-inflammatory M2 phenotype. However, the impact of MSC-macrophage inter...

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Bibliographic Details
Main Authors: Zhuang Cui, Yuan Feng, Danqing Li, Taoping Li, Peisong Gao, Ting Xu
Format: Article
Language:English
Published: Taylor & Francis Group 2020-01-01
Series:Journal of Immunotoxicology
Subjects:
Online Access:http://dx.doi.org/10.1080/1547691X.2019.1706671