The CCL5/CCR5 Axis Promotes Vascular Smooth Muscle Cell Proliferation and Atherogenic Phenotype Switching

The CCL5/CCR5 Axis Promotes Vascular Smooth Muscle Cell Proliferation and Atherogenic Phenotype Switching

Background/Aims: Hyperlipidemia induces dysfunction in the smooth muscle cells (SMCs) of the blood vessels, and the vascular remodeling that ensues is a key proatherogenic factor contributing to cardiovascular events. Chemokines and chemokine receptors play crucial roles in vascular remodeling. Here...

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Bibliographic Details
Main Authors: Chin-Sheng Lin, Po-Shiuan Hsieh, Ling-Ling Hwang, Yen-Hsien Lee, Shih-Hung Tsai, Yun-Chin Tu, Yao-Wen Hung, Cheng-Che Liu, Yi-Ping Chuang, Min-Tser Liao, Shu Chien, Min-Chien Tsai
Format: Article
Language:English
Published: Cell Physiol Biochem Press GmbH & Co KG 2018-05-01
Series:Cellular Physiology and Biochemistry
Subjects:
Vascular remodeling
Chemokine
Chemokine receptor
Smooth muscle cell proliferation
Phenotypic switching
Online Access:https://www.karger.com/Article/FullText/490024

Internet

https://www.karger.com/Article/FullText/490024

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