Search of Allosteric Inhibitors and Associated Proteins of an AKT-<i>like</i> Kinase from <i>Trypanosoma cruzi</i>

Search of Allosteric Inhibitors and Associated Proteins of an AKT-<i>like</i> Kinase from <i>Trypanosoma cruzi</i>

Proteins associated to the PI3K/AKT/mTOR signaling pathway are widely used targets for cancer treatment, and in recent years they have also been evaluated as putative targets in trypanosomatids parasites, such as <i>Trypanosoma cruzi</i>. Here, we performed a virtual screening approach t...

Full description

Bibliographic Details
Main Authors: Rodrigo Ochoa, Cristian Rocha-Roa, Marcel Marín-Villa, Sara M. Robledo, Rubén E. Varela-M
Format: Article
Language:English
Published: MDPI AG 2018-12-01
Series:International Journal of Molecular Sciences
Subjects:
<i>Trypanosoma cruzi</i>
protein kinase B
pleckstrin homology domain
drug discovery
Online Access:https://www.mdpi.com/1422-0067/19/12/3951

Internet

https://www.mdpi.com/1422-0067/19/12/3951

Similar Items