An Smp43-Derived Short-Chain α-Helical Peptide Displays a Unique Sequence and Possesses Antimicrobial Activity against Both Gram-Positive and Gram-Negative Bacteria

An Smp43-Derived Short-Chain α-Helical Peptide Displays a Unique Sequence and Possesses Antimicrobial Activity against Both Gram-Positive and Gram-Negative Bacteria

Scorpion venoms are rich resources of antimicrobial peptides (AMPs). While the short-chain noncysteine-containing AMPs have attracted much attention as templates for drug development, the antimicrobial potential of long-chain noncysteine-containing AMPs has been largely overlooked. Here, by using th...

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Bibliographic Details
Main Authors: Xudong Luo, Li Ding, Xiangdong Ye, Wen Zhu, Kaiyue Zhang, Fangyan Li, Huiwen Jiang, Zhiwen Zhao, Zongyun Chen
Format: Article
Language:English
Published: MDPI AG 2021-05-01
Series:Toxins
Subjects:
scorpion venom
noncysteine-containing AMPs
Smp43
Smp43(1-14)
antimicrobial resistance
HeliQuest
Online Access:https://www.mdpi.com/2072-6651/13/5/343

Internet

https://www.mdpi.com/2072-6651/13/5/343

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