Modaline sulfate promotes Oct4 expression and maintains self-renewal and pluripotency of stem cells through JAK/STAT3 and Wnt signaling pathways

Modaline sulfate promotes Oct4 expression and maintains self-renewal and pluripotency of stem cells through JAK/STAT3 and Wnt signaling pathways

Abstract Background Stem cells have been extensively explored for a variety of regenerative medical applications and they play an important role in clinical treatment of many diseases. However, the limited amount of stem cells and their tendency to undergo spontaneous differentiation upon extended p...

Full description

Bibliographic Details
Main Authors: Xianglin Mei, Hanhan Zhao, Huihan Ai, Shuyue Wang, Zhenbo Song, Lihua Zheng, Guannan Wang, Ying Sun, Yongli Bao
Format: Article
Language:English
Published: BMC 2021-08-01
Series:Cell & Bioscience
Subjects:
Modaline sulfate
Oct-4
Stem cell
Wnt signaling pathways
JAK/STAT3 signaling pathways
Online Access:https://doi.org/10.1186/s13578-021-00669-3

Internet

https://doi.org/10.1186/s13578-021-00669-3

Similar Items