Doxorubicin‐induced and trastuzumab‐induced cardiotoxicity in mice is not prevented by metoprolol

Abstract Aims Our objectives were to validate a murine model of chronic cardiotoxicity induced by Doxorubicin (Dox) and Trastuzumab (Trast) and to test the potential cardio‐protective effect of metoprolol. Methods and results Male C57Bl6 mice were intraperitoneally injected during 2 weeks with Dox (...

Full description

Bibliographic Details
Main Authors: Martin Nicol, Malha Sadoune, Evelyne Polidano, Jean Marie Launay, Jane Lise Samuel, Feriel Azibani, Alain Cohen‐Solal
Format: Article
Language:English
Published: Wiley 2021-04-01
Series:ESC Heart Failure
Subjects:
Online Access:https://doi.org/10.1002/ehf2.13198