Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing.

Spliceosomal Prp8 intein at the crossroads of protein and RNA splicing.

The spliceosome is a large ribonucleoprotein complex that removes introns from pre-mRNAs. At its functional core lies the essential pre-mRNA processing factor 8 (Prp8) protein. Across diverse eukaryotes, this protein cofactor of RNA catalysis harbors a self-splicing element called an intein. Inteins...

Full description

Bibliographic Details
Main Authors: Cathleen M Green, Zhong Li, Aaron D Smith, Olga Novikova, Valjean R Bacot-Davis, Fengshan Gao, Saiyang Hu, Nilesh K Banavali, Dennis J Thiele, Hongmin Li, Marlene Belfort
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2019-10-01
Series:PLoS Biology
Online Access:https://doi.org/10.1371/journal.pbio.3000104

Internet

https://doi.org/10.1371/journal.pbio.3000104

Similar Items