Mechanics of the IL2RA gene activation revealed by modeling and atomic force microscopy.

Mechanics of the IL2RA gene activation revealed by modeling and atomic force microscopy.

Transcription implies recruitment of RNA polymerase II and transcription factors (TFs) by DNA melting near transcription start site (TSS). Combining atomic force microscopy and computer modeling, we investigate the structural and dynamical properties of the IL2RA promoter and identify an intrinsical...

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Bibliographic Details
Main Authors: Pascale Milani, Monique Marilley, Albert Sanchez-Sevilla, Jean Imbert, Cédric Vaillant, Françoise Argoul, Jean-Marc Egly, José Rocca-Serra, Alain Arneodo
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3076448?pdf=render

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http://europepmc.org/articles/PMC3076448?pdf=render

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