ACE2 enhance viral infection or viral infection aggravate the underlying diseases

ACE2 enhance viral infection or viral infection aggravate the underlying diseases

ACE2 plays a critical role in SARS-CoV-2 infection to cause COVID-19 and SARS-CoV-2 spike protein binds to ACE2 and probably functionally inhibits ACE2 to aggravate the underlying diseases of COVID-19. The important factors that affect the severity and fatality of COVID-19 include patients' und...

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Bibliographic Details
Main Authors: Shaolei Teng, Qiyi Tang
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:Computational and Structural Biotechnology Journal
Subjects:
Coronavirus Infectious Disease-19
Severe Acute Respiratory Syndrome Coronavirus −2
Angiotensin converting enzyme 2
Single Nucleotide Polymorphism
Underlying diseases
Health disparity
Online Access:http://www.sciencedirect.com/science/article/pii/S200103702030355X

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http://www.sciencedirect.com/science/article/pii/S200103702030355X

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