IL-13 is a central mediator of chemical-induced airway hyperreactivity in mice.

IL-13 is a central mediator of chemical-induced airway hyperreactivity in mice.

While the importance of the Th2 cytokine IL-13 as a central mediator of airway hyperreactivity (AHR) has been described in allergic protein-induced asthma, this has never been investigated in chemical-induced asthma.We examined the importance of IL-13 in a mouse model of chemical-induced AHR, using...

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Bibliographic Details
Main Authors: Fien C Devos, Lore Pollaris, Jonathan Cremer, Sven Seys, Tomoaki Hoshino, Jan Ceuppens, Karel Talavera, Benoit Nemery, Peter H M Hoet, Jeroen A J Vanoirbeek
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2017-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC5509233?pdf=render

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http://europepmc.org/articles/PMC5509233?pdf=render

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