An analytical method for the identification of cell type-specific disease gene modules

Abstract Background Genome-wide association studies have identified genetic variants associated with the risk of brain-related diseases, such as neurological and psychiatric disorders, while the causal variants and the specific vulnerable cell types are often needed to be studied. Many disease-assoc...

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Bibliographic Details
Main Authors: Jinting Guan, Yiping Lin, Yang Wang, Junchao Gao, Guoli Ji
Format: Article
Language:English
Published: BMC 2021-01-01
Series:Journal of Translational Medicine
Subjects:
Online Access:https://doi.org/10.1186/s12967-020-02690-5