HER2-intronic miR-4728-5p facilitates HER2 expression and accelerates cell proliferation and migration by targeting EBP1 in breast cancer.

HER2-intronic miR-4728-5p facilitates HER2 expression and accelerates cell proliferation and migration by targeting EBP1 in breast cancer.

HER2 amplification greatly contributes to the tumorigenesis of multiple cancers. Intronic miR-4728-5p is transcribed along with its host gene HER2. However, little is known about the role of miR-4728-5p in cancer. This study aims to elucidate the potential role of miR-4728-5p and the underlying mech...

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Bibliographic Details
Main Authors: Yu Zhou, Yuan Yuan, Liuyi Li, Xueliang Wang, Yimin Quan, Chunyu Liu, Mengchao Yu, Xiuting Hu, Xiangfeng Meng, Zhen Zhou, Chen-Yu Zhang, Xi Chen, Minghui Liu, Chen Wang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2021-01-01
Series:PLoS ONE
Online Access:https://doi.org/10.1371/journal.pone.0245832

Internet

https://doi.org/10.1371/journal.pone.0245832

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