Dehydration affects drug transport over nasal mucosa

Formulations for nasal drug delivery often rely on water sorption to adhere to the mucosa, which also causes a higher water gradient over the tissue and subsequent dehydration. The primary aim of this study was therefore to evaluate mucosal response to dehydration and resolve the hypothesis that muc...

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Bibliographic Details
Main Authors: Abdullah Ali, Marie Wahlgren, Birgitta Rembratt-Svensson, Ameena Daftani, Peter Falkman, Per Wollmer, Johan Engblom
Format: Article
Language:English
Published: Taylor & Francis Group 2019-01-01
Series:Drug Delivery
Subjects:
Online Access:http://dx.doi.org/10.1080/10717544.2019.1650848