Basic Amino Acid Residues of Human Eosinophil Derived Neurotoxin Essential for Glycosaminoglycan Binding

Basic Amino Acid Residues of Human Eosinophil Derived Neurotoxin Essential for Glycosaminoglycan Binding

Human eosinophil derived neurotoxin (EDN), a granule protein secreted by activated eosinophils, is a biomarker for asthma in children. EDN belongs to the human RNase A superfamily possessing both ribonucleolytic and antiviral activities. EDN interacts with heparin oligosaccharides and heparin sulfat...

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Bibliographic Details
Main Authors: Margaret Dah-Tsyr Chang, Ping-Hsueh Kuo, Tan-chi Fan, Chien-Jung Chen, Hao-Teng Chang, Yuan-Chuan Lee, Ta-Jen Hung, Noboru Tomiya, Wei-Tang Chang
Format: Article
Language:English
Published: MDPI AG 2013-09-01
Series:International Journal of Molecular Sciences
Subjects:
eosinophil derived neurotoxin
heparin
glycosaminoglycan
heparin binding region
Online Access:http://www.mdpi.com/1422-0067/14/9/19067

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http://www.mdpi.com/1422-0067/14/9/19067

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