Basic Amino Acid Residues of Human Eosinophil Derived Neurotoxin Essential for Glycosaminoglycan Binding
Human eosinophil derived neurotoxin (EDN), a granule protein secreted by activated eosinophils, is a biomarker for asthma in children. EDN belongs to the human RNase A superfamily possessing both ribonucleolytic and antiviral activities. EDN interacts with heparin oligosaccharides and heparin sulfat...
Main Authors: | Margaret Dah-Tsyr Chang, Ping-Hsueh Kuo, Tan-chi Fan, Chien-Jung Chen, Hao-Teng Chang, Yuan-Chuan Lee, Ta-Jen Hung, Noboru Tomiya, Wei-Tang Chang |
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Format: | Article |
Language: | English |
Published: |
MDPI AG
2013-09-01
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Series: | International Journal of Molecular Sciences |
Subjects: | |
Online Access: | http://www.mdpi.com/1422-0067/14/9/19067 |
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