In vivo microstructural heterogeneity of white matter lesions in healthy elderly and Alzheimer's disease participants using tissue compositional analysis of diffusion MRI data

In vivo microstructural heterogeneity of white matter lesions in healthy elderly and Alzheimer's disease participants using tissue compositional analysis of diffusion MRI data

White matter hyperintensities (WMH) are regions of high signal intensity typically identified on fluid attenuated inversion recovery (FLAIR). Although commonly observed in elderly individuals, they are more prevalent in Alzheimer’s disease (AD) patients. Given that WMH appear relatively homogeneous...

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Bibliographic Details
Main Authors: Remika Mito, Thijs Dhollander, Ying Xia, David Raffelt, Olivier Salvado, Leonid Churilov, Christopher C. Rowe, Amy Brodtmann, Victor L. Villemagne, Alan Connelly
Format: Article
Language:English
Published: Elsevier 2020-01-01
Series:NeuroImage: Clinical
Subjects:
White matter hyperintensities
3-tissue
Heterogeneity
Diffusion MRI
Alzheimer’s disease
Online Access:http://www.sciencedirect.com/science/article/pii/S2213158220303168

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http://www.sciencedirect.com/science/article/pii/S2213158220303168

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