Pharmacokinetics of neutron-irradiated meglumine antimoniate in Leishmania amazonensis-infected BALB/c mice

Abstract Background: Cutaneous leishmaniasis (CL) is a parasitic disease caused by the protozoan Leishmania spp. Pentavalent antimonial agents have been used as an effective therapy, despite their side effects and resistant cases. Their pharmacokinetics remain largely unexplored. This study aimed...

Full description

Bibliographic Details
Main Authors: Samanta Etel Treiger Borborema, João Alberto Osso Junior, Heitor Franco de Andrade Junior, Nanci do Nascimento
Format: Article
Language:English
Published: SciELO 2019-03-01
Series:Journal of Venomous Animals and Toxins including Tropical Diseases
Subjects:
Online Access:http://www.scielo.br/scielo.php?script=sci_arttext&pid=S1678-91992019000100304&lng=en&tlng=en