Meningeal retinoic acid contributes to neocortical lamination and radial migration during mouse brain development

Retinoic acid (RA) is a diffusible molecule involved in early forebrain patterning. Its later production in the meninges by the retinaldehyde dehydrogenase RALDH2 coincides with the time of cortical neuron generation. A function of RA in this process has not been adressed directly as Raldh2−/− mouse...

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Bibliographic Details
Main Authors: Carole Haushalter, Brigitte Schuhbaur, Pascal Dollé, Muriel Rhinn
Format: Article
Language:English
Published: The Company of Biologists 2017-02-01
Series:Biology Open
Subjects:
Online Access:http://bio.biologists.org/content/6/2/148