Suppression of Gq function using intrapipette delivery of shRNA during extracellular recording in the ventral tegmental area

Selective suppression of protein function in the brain can be achieved using specific silencing RNAs administered in vivo. A viral delivery system is often employed to transfect neurons with shRNA directed against specific proteins, and intervals of several days are allowed between microinjection of...

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Bibliographic Details
Main Authors: Sudarat eNimitvilai, Devinder S. Arora, Maureen A. McElvain, Mark S. Brodie
Format: Article
Language:English
Published: Frontiers Media S.A. 2013-02-01
Series:Frontiers in Cellular Neuroscience
Subjects:
Gq
Online Access:http://journal.frontiersin.org/Journal/10.3389/fncel.2013.00007/full