Blood Cell-Bound C4d as a Marker of Complement Activation in Patients With the Antiphospholipid Syndrome

Blood Cell-Bound C4d as a Marker of Complement Activation in Patients With the Antiphospholipid Syndrome

Antiphospholipid syndrome (APS) is a chronic and disabling condition characterized by recurrent thrombosis and miscarriages mediated by antibodies against phospholipid-binding proteins (aPL), such as beta2glycoprotein I (β2GPI). Complement is involved in APS animal models and complement deposits hav...

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Bibliographic Details
Main Authors: Paola Adele Lonati, Mariangela Scavone, Maria Gerosa, Maria Orietta Borghi, Francesca Pregnolato, Daniele Curreli, Gianmarco Podda, Eti Alessandra Femia, Wilma Barcellini, Marco Cattaneo, Francesco Tedesco, Pier Luigi Meroni
Format: Article
Language:English
Published: Frontiers Media S.A. 2019-04-01
Series:Frontiers in Immunology
Subjects:
anti-phospholipid syndrome
beta2–glycoprotein I
complement
C4d
platelets
erythrocytes
Online Access:https://www.frontiersin.org/article/10.3389/fimmu.2019.00773/full

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https://www.frontiersin.org/article/10.3389/fimmu.2019.00773/full

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