Pharmacological alterations of anxious behaviour in mice depending on both strain and the behavioural situation.

A previous study comparing non-emotive mice from the strain C57BL/6/ByJ with ABP/Le mice showed ABP/Le to be more anxious in an open-field situation. In the present study, several compounds affecting anxiety were assayed on ABP/Le and C57BL/6/ByJ mice using three behavioural models of anxiety: the e...

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Bibliographic Details
Main Authors: Yan Clément, Anne-Marie Le Guisquet, Patrice Venault, Georges Chapouthier, Catherine Belzung
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2009-11-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC2770638?pdf=render