Gene expression and immune infiltration in melanoma patients with different mutation burden

Abstract Background Immunotherapy is a vital component in cancer treatment. However, due to the complex genetic bases of cancer, a clear prediction index for efficacy has not been established. Tumor mutation burden (TMB) is one of the essential factors that affect immunotherapeutic efficacies, but i...

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Bibliographic Details
Main Authors: Liwei Wang, Fu Chen, Rui Liu, Lei Shi, Guosheng Zhao, Zhengjian Yan
Format: Article
Language:English
Published: BMC 2021-04-01
Series:BMC Cancer
Subjects:
TMB
ICB
Online Access:https://doi.org/10.1186/s12885-021-08083-1