IGFBP3 impedes aggressive growth of pediatric liver cancer and is epigenetically silenced in vascular invasive and metastatic tumors
<p>Abstract</p> <p>Background</p> <p>Hepatoblastoma (HB) is an embryonal liver neoplasm of early childhood with a poor prognosis for patients with distant metastases and vascular invasion. We and others have previously shown that the overexpression of <it>insulin-...
Main Authors: | Regel Ivonne, Eichenmüller Melanie, Joppien Saskia, Liebl Johanna, Häberle Beate, Müller-Höcker Josef, Vollmar Angelika, von Schweinitz Dietrich, Kappler Roland |
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Format: | Article |
Language: | English |
Published: |
BMC
2012-03-01
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Series: | Molecular Cancer |
Subjects: | |
Online Access: | http://www.molecular-cancer.com/content/11/1/9 |
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