Proteolytic and Opportunistic Breaching of the Basement Membrane Zone by Immune Cells during Tumor Initiation

Summary: Cancer-related inflammation impacts significantly on cancer development and progression. From early stages, neutrophils and macrophages are drawn to pre-neoplastic cells in the epidermis, but before directly interacting, they must first breach the underlying extracellular matrix barrier lay...

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Bibliographic Details
Main Authors: Maaike C.W. van den Berg, Lucy MacCarthy-Morrogh, Deborah Carter, Josephine Morris, Isabel Ribeiro Bravo, Yi Feng, Paul Martin
Format: Article
Language:English
Published: Elsevier 2019-06-01
Series:Cell Reports
Online Access:http://www.sciencedirect.com/science/article/pii/S2211124719306400