Drug Resistance Driven by Cancer Stem Cells and Their Niche

Drug resistance represents one of the greatest challenges in cancer treatment. Cancer stem cells (CSCs), a subset of cells within the tumor with the potential for self-renewal, differentiation and tumorigenicity, are thought to be the major cause of cancer therapy failure due to their considerable c...

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Bibliographic Details
Main Authors: Marta Prieto-Vila, Ryou-u Takahashi, Wataru Usuba, Isaku Kohama, Takahiro Ochiya
Format: Article
Language:English
Published: MDPI AG 2017-12-01
Series:International Journal of Molecular Sciences
Subjects:
Online Access:https://www.mdpi.com/1422-0067/18/12/2574