Creating an Artificial 3-Dimensional Ovarian Follicle Culture System Using a Microfluidic System

Creating an Artificial 3-Dimensional Ovarian Follicle Culture System Using a Microfluidic System

We hypothesized that the creation of a 3-dimensional ovarian follicle, with embedded granulosa and theca cells, would better mimic the environment necessary to support early oocytes, both structurally and hormonally. Using a microfluidic system with controlled flow rates, 3-dimensional two-layer (co...

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Bibliographic Details
Main Authors: Mae W. Healy, Shelley N. Dolitsky, Maria Villancio-Wolter, Meera Raghavan, Alexandra R. Tillman, Nicole Y. Morgan, Alan H. DeCherney, Solji Park, Erin F. Wolff
Format: Article
Language:English
Published: MDPI AG 2021-03-01
Series:Micromachines
Subjects:
microfluidics
alginate
ovarian follicle
granulosa cell
theca cell
3D in vitro culture
Online Access:https://www.mdpi.com/2072-666X/12/3/261

Internet

https://www.mdpi.com/2072-666X/12/3/261

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