Voltage gated proton channels modulate mitochondrial reactive oxygen species production by complex I in renal medullary thick ascending limb

Hv1 is a voltage-gated proton channel highly expressed in immune cells where, it acts to maintain NAD(P)H oxidase activity during the respiratory burst. We have recently reported that Hv1 is expressed in cells of the medullary thick ascending limb (mTAL) of the kidney and is critical to augment reac...

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Bibliographic Details
Main Authors: Bansari Patel, Nadezhda N. Zheleznova, Sarah C. Ray, Jingping Sun, Allen W. Cowley, Jr., Paul M. O'Connor
Format: Article
Language:English
Published: Elsevier 2019-10-01
Series:Redox Biology
Online Access:http://www.sciencedirect.com/science/article/pii/S2213231719300060