Translating intracarotid artery transplantation of bone marrow‐derived NCS‐01 cells for ischemic stroke: Behavioral and histological readouts and mechanistic insights into stem cell therapy

Translating intracarotid artery transplantation of bone marrow‐derived NCS‐01 cells for ischemic stroke: Behavioral and histological readouts and mechanistic insights into stem cell therapy

Abstract The present study used in vitro and in vivo stroke models to demonstrate the safety, efficacy, and mechanism of action of adult human bone marrow‐derived NCS‐01 cells. Coculture with NCS‐01 cells protected primary rat cortical cells or human neural progenitor cells from oxygen glucose depri...

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Bibliographic Details
Main Authors: Yuji Kaneko, Jea‐Young Lee, Naoki Tajiri, Julian P. Tuazon, Trenton Lippert, Eleonora Russo, Seong‐Jin Yu, Brooke Bonsack, Sydney Corey, Alexandreya B. Coats, Chase Kingsbury, Thomas N. Chase, Minako Koga, Cesar V. Borlongan
Format: Article
Language:English
Published: Wiley 2020-02-01
Series:Stem Cells Translational Medicine
Subjects:
cell loss
cell transplantation
cerebral ischemia
cytokines
functional recovery
infarct
Online Access:https://doi.org/10.1002/sctm.19-0229

Internet

https://doi.org/10.1002/sctm.19-0229

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