A virus-free poly-promoter vector induces pluripotency in quiescent bovine cells under chemically defined conditions of dual kinase inhibition.

A virus-free poly-promoter vector induces pluripotency in quiescent bovine cells under chemically defined conditions of dual kinase inhibition.

Authentic induced pluripotent stem cells (iPSCs), capable of giving rise to all cell types of an adult animal, are currently only available in mouse. Here, we report the first generation of bovine iPSC-like cells following transfection with a novel virus-free poly-promoter vector. This vector contai...

Full description

Bibliographic Details
Main Authors: Ben Huang, Tong Li, Lucia Alonso-Gonzalez, Ruben Gorre, Sarah Keatley, Andria Green, Pavla Turner, Prasanna Kumar Kallingappa, Vinod Verma, Björn Oback
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2011-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3166309?pdf=render

Internet

http://europepmc.org/articles/PMC3166309?pdf=render

Similar Items