Modular composition of gene transcription networks.

Predicting the dynamic behavior of a large network from that of the composing modules is a central problem in systems and synthetic biology. Yet, this predictive ability is still largely missing because modules display context-dependent behavior. One cause of context-dependence is retroactivity, a p...

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Bibliographic Details
Main Authors: Andras Gyorgy, Domitilla Del Vecchio
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2014-03-01
Series:PLoS Computational Biology
Online Access:http://europepmc.org/articles/PMC3952816?pdf=render