L1pred: a sequence-based prediction tool for catalytic residues in enzymes with the L1-logreg classifier.

To understand enzyme functions, identifying the catalytic residues is a usual first step. Moreover, knowledge about catalytic residues is also useful for protein engineering and drug-design. However, to experimentally identify catalytic residues remains challenging for reasons of time and cost. Ther...

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Bibliographic Details
Main Authors: Yongchao Dou, Jun Wang, Jialiang Yang, Chi Zhang
Format: Article
Language:English
Published: Public Library of Science (PLoS) 2012-01-01
Series:PLoS ONE
Online Access:http://europepmc.org/articles/PMC3338704?pdf=render