Electroacupuncture Protects Cognition by Regulating Tau Phosphorylation and Glucose Metabolism via the AKT/GSK3β Signaling Pathway in Alzheimer’s Disease Model Mice

Electroacupuncture Protects Cognition by Regulating Tau Phosphorylation and Glucose Metabolism via the AKT/GSK3β Signaling Pathway in Alzheimer’s Disease Model Mice

BackgroundAlzheimer’s disease (AD) is mainly manifested as a continuous and progressive decline in cognitive ability. Neurofibrillary tangles (NFTs) are pathological hallmarks of AD and due to accumulated phosphorylated Tau. Glycogen synthase kinase-3β (GSK3β), as a major Tau kinase and a downstream...

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Bibliographic Details
Main Authors: Anping Xu, Qingtao Zeng, Yinshan Tang, Xin Wang, Xiaochen Yuan, You Zhou, Zhigang Li
Format: Article
Language:English
Published: Frontiers Media S.A. 2020-11-01
Series:Frontiers in Neuroscience
Subjects:
Alzheimer’s disease
electroacupucnture
cognition
glucose metabolism
tau
AKT/GSK3β pathway
Online Access:https://www.frontiersin.org/articles/10.3389/fnins.2020.585476/full

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https://www.frontiersin.org/articles/10.3389/fnins.2020.585476/full

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