Combination Therapy of Acarbose and Cyclosporine a Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice

Combination Therapy of Acarbose and Cyclosporine a Ameliorates Imiquimod-Induced Psoriasis-Like Dermatitis in Mice

Moderate to severe psoriasis, an immune-mediated inflammatory disease, adversely affects patients’ lives. Cyclosporin A (CsA), an effective immunomodulator, is used to treat psoriasis. CsA is ineffective at low doses and toxic at high doses. Acarbose (Acar), a common antidiabetic drug with anti-infl...

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Bibliographic Details
Main Authors: Hsin-Hua Chen, Chi-Chien Lin, Yu-Tang Tung, Ya-Hsuan Chao, Wen-Ching Huang, Po-Ying Lee
Format: Article
Language:English
Published: MDPI AG 2020-04-01
Series:Molecules
Subjects:
acarbose
cyclosporine
psoriasis
imiquimod
combination therapy
Online Access:https://www.mdpi.com/1420-3049/25/8/1822

Internet

https://www.mdpi.com/1420-3049/25/8/1822

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