Implication of lipoprotein associated phospholipase A2 activity in oxLDL uptake by macrophages
Recognition and uptake of oxidized LDL (oxLDL) by scavenger receptors of macrophages and foam cell formation are mediated by the oxidatively modified apolipoprotein B (ApoB) and lipid moiety of oxLDL. A great amount of oxidized phosphatidylcholine (oxPC) of oxLDL is hydrolyzed at the sn-2 position b...
Main Authors: | Konstantinos P. Markakis, Maria K. Koropouli, Stavroula Grammenou-Savvoglou, Ewoud C. van Winden, Andromaxi A. Dimitriou, Constantinos A. Demopoulos, Alexandros D. Tselepis, Eleni E. Kotsifaki |
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Format: | Article |
Language: | English |
Published: |
Elsevier
2010-08-01
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Series: | Journal of Lipid Research |
Subjects: | |
Online Access: | http://www.sciencedirect.com/science/article/pii/S0022227520370553 |
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