Sulfatide Preserves Insulin Crystals Not by Being Integrated in the Lattice but by Stabilizing Their Surface

Background. Sulfatide is known to chaperone insulin crystallization within the pancreatic beta cell, but it is not known if this results from sulfatide being integrated inside the crystal structure or by binding the surface of the crystal. With this study, we aimed to characterize the molecular mech...

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Bibliographic Details
Main Authors: Karsten Buschard, Austin W. Bracey, Daniel L. McElroy, Andrew T. Magis, Thomas Osterbye, Mark A. Atkinson, Kate M. Bailey, Amanda L. Posgai, David A. Ostrov
Format: Article
Language:English
Published: Hindawi Limited 2016-01-01
Series:Journal of Diabetes Research
Online Access:http://dx.doi.org/10.1155/2016/6179635