Bringing the Ca2+ sensitivity of myristoylated recoverin into the physiological range

The prototypical Ca2+-sensor protein recoverin (Rec) is thought to regulate the activity of rhodopsin kinase (GRK1) in photoreceptors by switching from a relaxed (R) disc membrane-bound conformation in the dark to a more compact, cytosol-diffusing tense (T) conformation upon cell illumination. Howev...

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Bibliographic Details
Main Authors: Valerio Marino, Matteo Riva, Davide Zamboni, Karl-Wilhelm Koch, Daniele Dell'Orco
Format: Article
Language:English
Published: The Royal Society 2021-01-01
Series:Open Biology
Subjects:
Online Access:https://royalsocietypublishing.org/doi/pdf/10.1098/rsob.200346