Intestinal Epithelial Barrier Maturation by Enteric Glial Cells is GDNF-Dependent

Intestinal Epithelial Barrier Maturation by Enteric Glial Cells is GDNF-Dependent

Enteric glial cells (EGCs) of the enteric nervous system are critically involved in the maintenance of intestinal epithelial barrier function (IEB). The underlying mechanisms remain undefined. Glial cell line-derived neurotrophic factor (GDNF) contributes to IEB maturation and may therefore be the p...

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Bibliographic Details
Main Authors: Michael Meir, Felix Kannapin, Markus Diefenbacher, Yalda Ghoreishi, Catherine Kollmann, Sven Flemming, Christoph-Thomas Germer, Jens Waschke, Patrick Leven, Reiner Schneider, Sven Wehner, Natalie Burkard, Nicolas Schlegel
Format: Article
Language:English
Published: MDPI AG 2021-02-01
Series:International Journal of Molecular Sciences
Subjects:
enteric glial cells
neurotrophic factors
intestinal epithelial barrier
GDNF5
RET6
inflammatory bowel disease
Online Access:https://www.mdpi.com/1422-0067/22/4/1887

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https://www.mdpi.com/1422-0067/22/4/1887

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